Appearance Infrared spectrometry Melting point 120°C - 125°C Purity ≥98.0% (GC) Water <0.5 % (K.F.) Heavy metals (as Pb) <10 ppm Sulfated ash <0.1 % Indole-3-carbaldehyde (I3A), also known as indole-3-aldehyde and 3-formylindole, is a metabolite of dietary l-tryptophan which is synthesized by human gastrointestinal bacteria, particularly species of the Lactobacillusgenus. I3A is a biologically active metabolite which acts as a receptor agonist at the aryl hydrocarbon receptor in intestinal immune cells, in turn stimulating the production of interleukin-22 which facilitates mucosal reactivity.